Your Drug Metabolism Guide

July 26th, 2010 by Angela

Drug metabolism consists of the sum of the biochemical processes through which medication is transformed by enzymes into substances that can be absorbed in the body system. The passage of the drugs through the body is very important for the very effect expected from a certain treatment. The very structure of the medications is pharmaceutically designed to correspond as well as doable to certain organic transformation that occur in the digestive tract, in the bloodstream and at the cellular level. The very fact that drugs are metabolized similarly leads to the appearance of interactions or reactions when more than one medication is administered.

The liver is the organ that answers for drug metabolism, even though the capability to metabolize drugs is specific to any living biological tissue. The high concentration of enzymes secreted by this organ makes the function of the organ more intense. When the pharmaceutical substance enters the hepatic circuit, there is a peak in the drug metabolism. Yet, other body parts play a part in chemical transformations and this happens with the gastrointestinal tract, the kidneys or the skin. The only inconvenience for this form of more extensive metabolism, is in the toxicity reactions and the doable side effects.

Drug metabolism can vary depending on some pathological and physiological factors, and these need to be taken into consideration when a specific medication is prescribed. Thus, the condition of the intestinal flora, sex and age differences, nutrition and other doable diseases influence drug metabolism in more than one way.

Heart, liver and kidney disease represent the most troublesome pathological factors that interfere with drug metabolism. Therefore, it is of paramount importance that any unknown health condition be reported to the health care bourgeois before the beginning or the choice of a treatment. Moreover, do specify if you take any other medication because there might be interactions as well.

Finally, even though it might seem unimportant or irrelevant for a patient, some knowledge on drug metabolism could help you comprehend how medication works on the body system. Moreover, it could help one prevent or minimize some nasty side effects.

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